Clinical Trial Results Archive

Clinical Trial Results: August 2008

August 1 Lux Presents Data at ARVO on LX214 as Potential Treatment for Dry Eye
August 1 Lab Study Shows Methadone Breaks Resistance in Untreatable Forms of Leukemia
August 1 MDRNA, Inc. Demonstrates In Vivo Efficacy with Proprietary DiLA2 Delivery Platform
August 1 Immunotherapy in High-Risk Pediatric Sarcomas Shows Promising Response
August 1 MDRNA Announces Phase 2 Trial of PYY(3-36) Does not Meet Weight Loss Endpoint
August 1 A Long Lasting Impression: New Study Find Persistent Brain Changes in Response to Cocaine Depend on the Expectation of Reward NIDA
August 1 Preclinical Data for a Topical Formulation of Voclosporin as a Potential Best-in-Class Treatment for Chronic Inflammatory Eye Diseases Presented at ARVO
August 4 Karo Bio Announces Successful Phase II Study with Eprotirome in Combination with Statin
August 4 Suven Life Sciences Presents Positive Preclinical Data for SUVN-502 at Alzheimer's Conference, Chicago and Drug Discovery Conference, Boston
August 4 Amicus Therapeutics Announces Successful Completion of End of Phase 2 Meeting With FDA for Amigal in Fabry Disease
August 4 Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
August 4 HIV Treatment Widely-Used in Developing Countries May Be Less Effective When Used With Anti-TB Therapy
August 4 Growth Hormone Treatment for HIV-Related Abdominal Obesity Improves Abdominal Fat and Other Cardiovascular Measures, but May Be Limited By Effects on Glucose
August 4 Highly Active Antiretroviral Therapy of Similar Benefit for HIV-Infected Injection Drug Users
August 4 Turned-Off Cannabinoid Receptor Turns on Colorectal Tumor Growth
August 4 New Long-Term Prospective Study of Statin Drugs Confirms Utility To Reduce Risk of Dementia and Memory Loss
August 4 New Research Results Explain How Dormant Tumor Cells Become Active in Later Years
August 4 Leukemia Journal Publishes Results from Darinaparsin Study
August 4 Theratechnologies Reports on Positive Body Image Parameters at the International AIDS Conference
August 5 YM BioSciences Reports Phase II Data for Nimotuzumab Metastatic Colorectal Cancer
August 5 Pharmasset Reports Preliminary Results of a 4-week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
August 5 Cara Therapeutics Announces Successful Completion of Phase I Clinical Trial of Novel Analgesic, CR845
August 5 Xanodyne Achieves Positive Efficacy Results in Pivotal Phase 3 Studies of Proprietary Modified Release Oral Tranexamic Acid Product Candidate for Heavy Menstrual Bleeding
August 5 Rib-X Pharmaceuticals, Inc. Announces Recent and Upcoming Presentations at Scientific Conferences
August 5 Orthokine Treatment is Effective for Knee Arthritis, Even After Two Years
August 5 Urologists Should Recognize the Cardiac Safety of Prescribed Medications, Article Concludes
August 5 Treatment With Anti-Anemia Drugs May Not Be Safe For Multiple Myeloma Patients
August 5 MIV Announces Excellent Safety and Efficacy of VESTAsync Polymer-Free Drug-Eluting Stent at 12-Month Clinical Follow Up
August 5 YM Biosciences Conference Call to Discuss Phase II Data for Nimotuzumab in Metastic Colorectal Cancer
August 5 CASTLE Data Showed Boosted Reyataz (atazanavir sulfate) and Lopinavir/r Achieved Similar Results for Undetectable Viral Load in Treatment-Naive HIV-1 Infected Patients, Regardless of Gender
August 5 Ninety-Six Week Data on Tibotec Investigational NNRTI, TMC278, Presented at AIDS 2008
August 5 Isentress (raltegravir), Merck's First in Class Integrase Inhibitor, Reduced HIV Viral Load and Increased CD4 Cell Counts Through 96 Weeks in Treatment-Naive HIV-Infected Patients When Taken With Other Anti-HIV Medicines
August 5 Abbott's Kaletra Tablet Dosed Once-Daily or Twice-Daily Demonstrated Similar Clinical Results Across Race and Gender Lines
August 5 Stanford Study Finds HIV Drug Can Persist in Mothers' Milk, Increasing Risk to Them and Their Babies
August 6 CASTLE Data Showed Boosted Reyataz (atazanavir sulfate) and Lopinavir/r Achieved Similar Results for Undetectable Viral Load in Treatment-Naive HIV-1 Infected Patients, Regardless of Gender
August 6 Dynavax and Merck & Co., Inc. Announce Phase 3 Trial with Investigational Hepatitis B Vaccine (HEPLISAV) Met its Primary Endpoint
August 6 Isolagen, Inc. Reports Positive Top-line Results from Pivotal Phase III Studies of Isolagen Therapy(TM) in Wrinkles: Studies Meet All Primary Efficacy Endpoints and are Statistically Significant
August 6 Inspire Announces Peer-Reviewed Publications Related to Denufosol for Cystic Fibrosis
August 6 Protherics Plc DEEP Results in Pre-Eclampsia to be Presented at Leading Conference
August 6 Cortex's AMPAKINE Molecule CX717 Has Positive Effects in Opiate-Induced Respiratory Depression in a Phase IIa Clinical Study
August 6 Mesoblast Limited (ASX:MSB); Non-healing Bones Repaired II Clinical Trial Using Adult Stem Cells
August 6 Oramed Pharmaceuticals Announces Successful Phase 2A Clinical Trial of its Oral Insulin Capsule
August 6 Pooled-Analysis of 54 Clinical Studies Shows No Increased Risk of Heart Attack With Abacavir Therapy
August 6 Genetic Biomarker Linked to Subcutaneous Growth Hormone Dose-Response
August 6 Lipitor 80 mg Reduced the Risk of Heart Attack and Stroke in Patients with Heart Disease, Type 2 Diabetes and Chronic Kidney Disease
August 7 Ondine Announces Publication of Positive Results from Pseudomonas aeruginosa Eradication Study
August 7 Nature Publication Reports on Key Role of Bile Acids in Glucose Metabolism and Insulin Signaling
August 7 New Survey Explores the Impact of Insulin Injections and Communications Between Patients and Healthcare Providers
August 7 New Prostate Cancer Test is Ready for Commercialization Following Successful Completion of Final Clinical Trials
August 7 Argos Therapeutics' Arcelis Personalized Immunotherapy Platform in HIV Achieves Primary Endpoint in Phase 1 Trial
August 7 Mesoblast Limited (ASX:MSB) National Media Coverage Focused on Results of Adult Stem Cell Bone Repair Trial
August 7 IMPAX Reports Positive Results in Phase III Trial with IPX056
August 7 Head-to-Head 96-Week Study Shows Epizcom is Comparable to Truvada in Efficacy and Safety Measures in HIV Treatment-Naive Patients
August 7 Analysis of Six Clinical Trials Finds Epzicom Effective in Treatment-Naive HIV Patients With Both High and Low Baseline Viral Loads
August 7 Macular Degeneration Risk Studied in an Asian Population; Time Spent Outdoors Impacts Nearsightedness in Children; and Two Treatments to Combat Ocular Surface Cancer
August 7 Ardea Biosciences Presents Phase 2a Antiviral Activity Data for Lead HIV Candidate, RDEA806 at XVII International AIDS Conference
August 8 Abbott Study Shows Investigational Heat-Stable Norvir(R) Tablet Provides Similar Drug Levels to Current Norvir Capsule
August 8 Santhera Provides Update on Clinical/Regulatory Processes with SNT-MC17/Idebenone for the Treatment of Friedreich's Ataxia
August 11 NanoViricides, Inc. Reports that HIVCide-I Was Significantly Superior to the Current Anti-HIV Three Drug Cocktail Standard
August 11 Altus Pharmaceuticals Announces Achievement of Primary Endpoint in Phase 3 Efficacy Trial of Trizytek for Cystic Fibrosis Patients with Pancreatic Insufficiency
August 12 Alnylam and Collaborators Publish New Preclinical Research on RNAi-Mediated Silencing of PCSK9
August 12 Losing Weight After Diabetes Diagnosis can Prevent Diabetes-Related Disease, Kaiser Permanente Study Finds
August 12 Dicerna Pharmaceuticals' Co-founders Publish Studies Describing Novel Approaches to Maximizing Dicer-Substrate Small Interfering RNAs (DsiRNAs)
August 12 Javelin Presents PMI-150 (Intranasal Ketamine) Data at Premier Department of Defense Scientific Meeting
August 12 VitiGam Inhibits Melanoma Growth in a Dose Dependent Manner
August 12 Bronchitol Cystic Fibrosis Dose Trial Results Positive
August 12 Canopus Biopharma and Leading Chinese Researcher Team Up to Treat Avian Influenza, to Prevent Possible Pandemic
August 12 Mesoblast Limited Stem Cells Regrow Knee Cartilage in Severe Post-Menopausal Osteoarthritis
August 12 Cholesterol Drug Plays Role in Melanoma Remission
August 12 Experimental Chemotherapy Regimen Shows Promise in Treating Advanced Lung Cancer
August 12 Risk Assessment Plays Key Role in Long-Term Treatment of Breast Cancer
August 13 NewCardio Announces Positive Results From Third Clinical Validation Study
August 13 MDRNA, Inc. Lead Candidate Demonstrates In Vivo Efficacy against Seasonal and Pandemic Flu Strains
August 13 Nasal Hepatitis B Vaccine Elicits Robust Immunity With a Single Dose; Confers Major Advantages Over Traditional Vaccines
August 13 Obesity, Previous Use of HRT, and Treatment with Aromatase Inhibitors Puts Postmenopausal Women with Early-Stage Breast Cancer at Increased Risk of Joint Symptoms
August 13 NIH Scientists Find a Novel Mechanism that Controls the Development of Autoimmunity
August 13 i3 Drug Safety to Deliver 17 Presentations at ICPE 2008
August 14 Palatin Technologies, Inc. Reports Positive Results of Phase 2a Clinical Study with PL-3994 for the Treatment of Heart Failure
August 14 Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172
August 14 Probiodrug to Present Potential New Treatment for Alzheimer’s Disease
August 14 New Study Highlights Importance for Women to Know Their Risk of Heart Disease
August 14 Nuvelo Announces Positive Phase 1b Proof-of-Concept Data With Anticoagulant NU172
August 14 Nutra Pharma Announces Initial Positive Safety Data from Clinical Study in Adrenomyeloneuropathy (AMN)
August 14 'Protein Complementarity' May Offer New Insights Into Autoimmune Diseases
August 14 Micromet Data Show Tumor Regressions in Relapsed Lymphoma Patients Treated with T Cell Engaging BiTE Antibody Blinatumomab
August 14 Researchers Find Leishmaniasis Parasites Evade Death by Exploiting the Immune Response to Sand Fly Bites
August 15 Antisoma plc: Evidence of Activity Seen in New Data from ASA404 Prostate Cancer Trial
August 15 Alternative Vaccine Strategy Shows Promise in Prostate Cancer Patients
August 15 Treatment with Plerixafor Shown to Improve Mobilization of Cells in Donors During Bone Marrow Stem Cell Collection Procedures
August 15 Giving Heart Attack Patients Anticlotting Drug Tirofiban in Ambulance Improves Clinical Outcome in Hospital (On-TIME 2 Study)
August 15 Combination Therapy Reduces Proteinuria More Than Single Drugs but causes More Kidney Damage (ONTARGET STUDY)
August 18 Repros Therapeutics Inc. Provides Update for US Phase II Endometriosis Study and Completion of QT Interval Dose Selection Screen
August 18 Micromet, Inc. to Host Webcast and Conference Call to Discuss Blinatumomab Data Published in SCIENCE
August 18 Dyax Announces DX-88 for Hereditary Angioedema Meets Primary and Secondary Endpoints in Phase 3 Trial (EDEMA4(R))
August 18 Logical Therapeutics Inc. Announces Results of Phase 1b Clinical Study of its Naproxen Prodrug
August 18 Prescription Sleeping Pill Use Tied to Cancer
August 18 Use of Conventional Antipsychotics Medications Linked to Increased Risk of Cardiovascular, Respiratory Disease Deaths in Elderly Patients
August 19 Regeneron and Bayer HealthCare Announce VEGF Trap-Eye Achieved Durable Improvement in Vision over 52 Weeks in a Phase 2 Study in Patients with Age-Related Macular Degeneration
August 19 Afid Therapeutics Inc.'s New Anticoagulant Heparin Replacement Passes in Vivo Test
August 19 Regulus Therapeutics and Collaborators Publish New Data on a Critical Role for miR-21 in Brain Tumors
August 19 Pain Therapeutics and King Pharmaceuticals Announce Final Data of Remoxy Phase III Study at World Pain Congress in Scotland
August 19 Journal of Cardiovascular Electrophysiology Publishes Data Showing Ranolazine Shortened QT Interval and Improved Cardiac Relaxation in Study of Patients With Long QT Syndrome
August 19 New Data Show Prolonged Release Oxycodone/Naloxone Provides Effective Pain Relief and Reduces OIC in Patients with Severe Chronic Pain
August 19 Hayes Evaluates Test and Treatment Options for Attention-Deficit Hyperactivity Disorder
August 19 Bacterial Pneumonia Caused Most Deaths in 1918 Influenza Pandemic Implications for Future Pandemic Planning
August 19 Viral Genetics, Inc. Unveils Potential Mechanism of Action in HIV/AIDS Research, Accepted to Present Findings at Prestigious IHV Meeting
August 19 Clinical-Scale Generation of Functional Red Blood Cells from Human Embryonic Stem Cells
August 20 12 Month Phase 3 Trial Finds Bronchitol Safe in Bronchiectasis
August 20 Positive Findings Published on Emergent Technology for Treating Chronic Pain
August 20 TheraQuest Presents Topical Local Anesthetic and Abuse Deterrence Data at the World Congress on Pain
August 21 Vaxfectin-formulated Measles DNA Vaccine Could Address Unmet Need for Infants
August 21 Repros Therapeutics Inc. Announces No Tumors in First Completed Proellex Animal Carcinogenicity Study
August 21 PTC124 Shows Promising Activity in Cystic Fibrosis; Phase 2 Proof-of-Concept Data Published in the Lancet
August 21 Metvix Prevents Pre-cancerous Lesions in Transplant Patients
August 21 Head-to-Head Study Showed Prasugrel Statistically Superior to Clopidogrel in Reducing Recurrent Cardiovascular Events
August 21 Novavax to Present Phase I/IIa Trial Data Results in an Investor Conference Call on August 26, 2008
August 21 Catalyst Pharmaceutical Partners Announces Publication of Animal Data Demonstrating Vigabatrin Effective for Weight Loss
August 21 Javelin Presents Successful Pivotal Phase 3 Secondary Clinical Results for Dyloject at the 12th World Congress on Pain
August 21 Kamada Successfully Completes Phase II Trial with Aerosolized AAT in Cystic Fibrosis Patients
August 21 VaxInnate's M2e Universal Influenza Vaccine Candidate Demonstrates Safety and Immunogenicity in Phase I Clinical Study
August 21 New Drug for Cystic Fibrosis Bypasses Genetic Defect and Improves Cell Membrane Function
August 22 ARYx Therapeutics, Inc. Announces Successful Results of Chronic Constipation Clinical Trial on ATI-7505
August 22 Telik's Proteasome Inhibitor Program Meets a Preclinical Development Milestone
August 22 Synta Announces Publication of Elesclomol Mechanism of Action Results in AACR Journal Molecular Cancer Therapeutics
August 22 Mesoblast Limited's (ASX:MSB) Allogeneic, "Off-The-Shelf", Stem Cells Are Safe And Effective For Cervical Spine Fusion
August 25 Patients Taking Cymbalta Experienced Reduced Chronic Low Back Pain in New Study
August 25 Extensively Drug-resistant Tuberculosis Can be Managed with Aggressive Treatment Strategy
August 25 NicOx Provides Update on PF-03187207 and the Ongoing Research Collaboration with Pfizer
August 25 Isolagen Reports Positive Results from Open Label, Phase II Study of Isolagen Therapy of the Full Face Regarding the Treatment of Wrinkles and Skin Quality Characteristics
August 25 Role of pramipexole in key research areas of Parkinson’s disease management discussed at 12th EFNS Congress
August 26 ADAGIO Trial Results Show Teva's Azilect 1 mg Tablets Slow Progression of Parkinson's Disease
August 26 More Evidence Published That Epidemics of Childhood Obesity, Type 2 Diabetes and Metabolic Syndrome are Linked to Immunization
August 26 Infections Linked to Premature Births More Common Than Thought, Stanford Study Finds
August 26 NeuroDiscovery Ltd: NSL-101 Demonstrates Effective Pain Relief in Phase IIa Trial
August 26 Pharmalink Reports Positive Phase III Results for Xepol, a Treatment for Post-Polio Syndrome
August 26 Novavax Announces Favorable Results from Phase I/IIa Pandemic Influenza Vaccine Program
August 26 XTENT Announces CUSTOM II Data Selected for Publication in EuroIntervention
August 26 Omeros Announces Publication of Clinical Results for OMS103HP in Arthroscopy: The Journal of Arthroscopic and Related Surgery
August 26 Pramipexole Clinical Trial Programme in Restless Legs Syndrome (RLS) Reveals New Significant Results
August 26 New Publication Shows Cleviprex is Safe and Effective for Treatment of Acute, Severe Hypertension
August 26 Professor John F. Thompson to Present at Perspectives in Melanoma XII, Thursday October 2, 2008
August 26 Early Trigger for Type-1 Diabetes Found in Mice, Stanford Scientists Report
August 26 ACUITY 1-Year Sub-Analysis Published in Journal of the American College of Cardiology
August 26 SF1126, Semafore's PI3 Kinase Inhibitor, Found to Block Angiogenic Signaling From Both VEGF and Bv8 in Multiple Cell Lines
August 26 Individuals With History of Nonmelanoma Skin Cancer at Greater Risk for Future Cancers
August 27 Bristol-Myers Squibb and Pfizer Provide Update on Apixaban Clinical Development Program
August 27 Ark’s Vitor commences patient enrolment into Phase III pilot study
August 27 Semafore Broadens Pipeline With Multi-Targeted Kinase Inhibitors
August 27 Photocure Announces Positive Phase II Results with Visonac for Acne
August 27 Curis Announces Nature Publication Elucidating a Paracrine Mechanism of Action in Hedgehog-Expressing Tumors
August 27 Stallergenes: New Study VO 56 Highly Positive Results Conducted in an Allergen Challenge Chamber
August 28 Algeta Reports Positive Headline Phase II Data on Pain Palliation With Alpharadin
August 28 The University of Nottingham in the British Midlands Announces Breakthrough in Parkinson's Disease Research
August 28 National Study Shows Magnesium Sulfate Reduces Risk of Cerebral Palsy in Premature Births
August 28 New England Journal of Medicine Publishes Phase III Results of Velcade (Bortezomib) for Injection in Previously Untreated Multiple Myeloma Patients
August 28 ThermoDox Liver Cancer Study Phase I Results to Be Presented at ILCA Conference 2008
August 28 The Cypher Sirolimus-eluting Coronary Stent Outperforms the Taxus Stent in People with Diabetes
August 28 Alseres Pharmaceuticals Announces Preclinical Study Results Demonstrating that Rho Inhibitors Could Be Useful in Promoting Bone Healing
August 28 Academic Publication Highlights Method for Stabilizing the Adenosine A2a G-protein Coupled Receptor for Drug Discovery Studies
August 28 Low Levels of Brain Chemical May Lead to Obesity, NIH Study of Rare Disorder Shows
August 28 Oral Tolerability of Cysteine-Rich Protein Isolate (Immunocal) in Autism - A Pilot Study

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