nicorette and Exelon Interactions

Interactions between nicorette(nicotine) and Exelon (rivastigmine)

nicotine and rivastigmine (Minor Drug-Drug)

The manufacturer has reported that nicotine use increases the oral clearance of rivastigmine by 23%. The mechanism of this interaction has not been reported. Because the dose of rivastigmine is individually titrated to tolerability, no specific rivastigmine dosage adjustments are recommended.