Diupres Side Effects

Please note - some side effects for Diupres may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

For the professional

Diupres

The following adverse reactions have been reported and, within each category, are listed in order of decreasing severity.

Chlorothiazide

Body as a Whole: Weakness.

Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics or antihypertensive drugs).

Digestive: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia.

Hematologic: Aplastic anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia.

Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.

Metabolic: Electrolyte imbalance, hyperglycemia, glycosuria, hyperuricemia.

Musculoskeletal: Muscle spasm.

Nervous System/Psychiatric: Vertigo, paresthesias, dizziness, headache, restlessness.

Renal: Renal failure, renal dysfunction, interstitial nephritis.

Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia.

Special Senses: Transient blurred vision, xanthopsia.

Urogenital: Impotence.

Reserpine

Cardiovascular: Angina pectoris, arrhythmia, premature ventricular contractions, other direct cardiac effects (e.g., fluid retention, congestive heart failure), bradycardia.

Digestive: Vomiting, diarrhea, nausea, hypersecretion and increased motility, anorexia, dryness of mouth, increased salivation.

Hematologic: Thrombocytopenia purpura, excessive bleeding following prostatic surgery.

Hypersensitivity: Pruritis, rash, flushing of skin.

Metabolic: Weight gain.

Musculoskeletal: Muscular aches.

Nervous System/Psychiatric: Mental depression, dull sensorium, syncope, paradoxical anxiety, excessive sedation, nightmares, headache, dizziness, nervousness, parkinsonism (usually reversible with decreased dosage or discontinuance of therapy).

Respiratory: Dyspnea, epistaxis, nasal congestion, enhanced susceptibility to colds.

Special Senses: Optic atrophy, uveitis, deafness, glaucoma, conjunctival injection, blurred vision.

Urogenital: Dysuria, impotence, decreased libido, nonpuerperal lactation.

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